Droplet-based Liquid-liquid Extraction and On-chip Ir-waveguide-spectroscopy Detection of Cocaine in Human Saliva

نویسندگان

  • Philip Wägli
  • Yu-Chi Chang
  • Alexandra Homsy
  • Lubos Hvozdara
  • Peter D. van der Wal
  • Hans Peter Herzig
  • Nico F. de Rooij
چکیده

We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with the on-chip cocaine detection by IR-waveguide-spectroscopy (QC-laser, waveguide, detector). With our droplet-based extraction method we achieve an additional analyte pre-concentration of at least two orders of magnitude.

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تاریخ انتشار 2012